What if trypsin is located in the extracellular ghost medium

Experiments with erythrocyte “ghosts” were carried out to learn more about the glucose transporter in red blood cells. “Ghosts” are prepared by lysing red blood cells in a hypotonic medium and washing away the cytoplasmic contents. Suspension in an isotonic buffer allows the ghost membranes to reseal. If ghosts are prepared so that the enzyme trypsin is incorporated into the ghost interior, glucose transport does not occur. But glucose transport is not affected if trypsin is located in the extracellular ghost medium. What can you conclude about the glucose transporter, given these observations?

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