Solution-Addition of glutamate and glycine

A complete motor neuron is removed from a frog and placed in a large volume of modified extracellular saline. The neuron is healthy; it has a stable resting voltage of -70 millivolts. It is not producing any action potentials; its threshold for an action potential is -50 millivolts. The only ligand-gated Receptors in the neuron’s plasma membrane are AMPA Receptors, GABAA Receptors, GABAB Receptors, and glycine Receptors. The equilibrium potential for chloride ions is -70 millivolts, the equilibrium potential for potassium ions is -70 millivolts, and the equilibrium potential for sodium ions is +60 millivolts.

A. The addition of glutamate and glycine to the physiological saline will lead to an increase in the amount of intracellular sodium, a decrease in the amount of intracellular potassium, and to an increase in the amount of intracellular chloride.

B. The addition of GABA to the physiological saline will lead to an increase in the amount of intracellular chloride and a decrease in the amount of intracellular potassium.

C. The addition of glutamate and GABA to the physiological saline will lead to no net change in the amount of intracellular chloride.

D. A and B.

E. A and C.

F. B and C.

G. A, B, and C.

H. None of the above.

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