Healthcare institutions continue to face challenges in providing safe patient care in increasingly complex organizational and regulatory environments while striving to maintain financial viability. The clinical microsystem provides a conceptual and practical framework for approaching organizational learning and delivery of care. However, conflict exists between the conceptual theory and the daily practical applications of providing safe and effective care within healthcare systems. What are some conflicts that you may have observed, or think may exist between the conceptual theory of the clinical microsystem and every day practice in the clinical setting? The microsystem unit allows leaders to embed quality and safety into a microsystemâ€™s developmental journey. Leaders can set the stage for making safety a priority for the organization while allowing individual microsystems to create innovative strategies for improvement. Remember, leaders include formal, informal and on-the-spot leaders. What are some ways that leaders in a microsystem unit can make safety a priority while still allowing creative, innovative strategies for improvement?